期刊
JOURNAL OF CRANIO-MAXILLOFACIAL SURGERY
卷 38, 期 8, 页码 601-604出版社
CHURCHILL LIVINGSTONE
DOI: 10.1016/j.jcms.2010.01.008
关键词
cellular blue nevus (CBN) lymph node metastases; no malignant transformation; no primary skin-lesion
A case of cervical lymph node infiltration by a benign cellular blue nevus (CBN) and a 27-year disease history is presented Dermal dendritic melanocytes and pigmented spindle cells presented no histological evidence of malignancy (CD34-, desmin-, PanCy-, HMB-45+, anti-S-100+, Bcl-2+, MART-1+, focally expression of melan A, 1% Ki-67+ of the tumour cell nucleoli) The differentiation of the benign blue nevus (BN) from a malignant blue nevus (MBN) and a malignant melanoma (MM) is still a challenge Because of the malignant transformation potential of 5 2-6 3% a histological examination and a conservative surgical approach with close follow up are mandatory (C) 2010 European Association for Cranio-Maxillo-Facial Surgery
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