期刊
JOURNAL OF CONTROLLED RELEASE
卷 185, 期 -, 页码 12-21出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.jconrel.2014.04.018
关键词
Electrospinning; Drug delivery; Wound dressing; Local chemotherapy
资金
- National Natural Science Foundation of China [91227118, 51373167]
Electrospinning has been recognized as a simple and versatile method for fabrication of polymer nanofibers. Various polymers that include synthetic, natural, and hybrid materials have been successfully electrospun into ultrafine fibers. The inherently high surface to volume ratio of electrospun fibers can enhance cell attachment, drug loading, and mass transfer properties. Drugs ranging from antibiotics and anticancer agents to proteins, DNA, RNA, living cells, and various growth factors have been incorporated into electrospun fibers. This article presents an overview of electrospinning techniques and their application in drug delivery. (C) 2014 Elsevier B.V. All rights reserved.
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