期刊
JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY
卷 33, 期 6, 页码 844-850出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/RCT.0b013e3181a7e3c7
关键词
liver neoplasms; magnetic resonance (MR); contrast media; computed tomography (CT); technology
资金
- National R&D Program for Cancer Control, Ministry of Health and Welfare, Republic of Korea [0620220]
Purpose: The aim of this study was to compare the diagnostic accuracy and sensitivity of gadoxetic acid-enhanced magnetic resonance imaging (MRI) with multi-detector row computed tomography (MDCT) for the detection of hepatocellular carcinomas (HCCs). Materials: Sixty-two patients (81 HCCs) who underwent MDCT and gadoxetic acid-enhanced MRI using a 3-dimensional volumetric interpolated technique with a mean interval of 7 days (range, 3-11 days) were included in this study. Two observers reached a consensus on. 2 sets of images: the gadoxetic acid set (unenhanced, early dynamic, 10-minute, and 20-minute hepatocyte phase images) and the 3-phase MDCT Diagnostic accuracy and sensitivity were evaluated using the alternative-free response receiver operating characteristic method. Results: There was a trend toward increased area under the receiver operating characteristic curve (Az value) for the gadoxetic acid set (0.963) as compared with the MDCT (0.930), but no significant difference was found (P = 0.41). Sensitivity of the gadoxetic acid set (91.4%) was better than that of the MDCT (71.6%; P = 0.0001). There were 12 lesions that showed only arterial hypervascularization on MDCT but showed arterial hypervascularization and delayed hypointensity on the gadoxetic acid set. Conclusions: Gadoxetic acid-enhanced MRI, including hepatocyte phase imaging, is more sensitive than MDCT for the detection of HCCs.
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