期刊
JOURNAL OF COLLOID AND INTERFACE SCIENCE
卷 358, 期 2, 页码 626-634出版社
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.jcis.2011.03.039
关键词
Electrostatic adsorption; Self-assembly; Thin films; OLA; dsDNA; QCM-D
资金
- Fundacao para a Ciencia e a Tecnologia (FCT) [SFRH/BD/47622/2008, SFRH/BD/45492/2008, SFRH/BD/39279/2007]
- FEDER [PTDC/QUI/69685/2006]
- Fundação para a Ciência e a Tecnologia [SFRH/BD/47622/2008, SFRH/BD/39279/2007, SFRH/BD/45492/2008, PTDC/QUI/69685/2006] Funding Source: FCT
Thin films composed of oleylamine (OLA) and double-stranded deoxyribonucleic acid (dsDNA from Salmon testes) have been successfully constructed on polycrystalline Au surfaces using the electrostatic adsorption and self-assembly (SA) technique. The formation of the Au/OLA/dsDNA films was followed step-by-step by Quartz Crystal Microbalance with energy dissipation (QCM-D), Atomic Force Microscopy (AFM), and electrochemical techniques such as Cyclic Voltammetry (CV) and Electrochemical Impedance Spectroscopy (EIS). The use of these techniques allowed the characterization and the follow up of the successful construction of the OLA/dsDNA composite film. The main advantages of the proposed methodology are the simplicity of the modification procedure, the stability of the dsDNA self-assembled film, and the potential employment of the dsDNA modified gold electrodes to study the interactions of DNA with target molecules. Copyright (C) 2011 Elsevier Inc. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据