期刊
JOURNAL OF COLLOID AND INTERFACE SCIENCE
卷 350, 期 2, 页码 402-408出版社
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.jcis.2010.06.052
关键词
Silver nanoparticles; Titanium; Implants; Antibacterial; Pseudomonas aeruginosa
资金
- ANPCyT [PICT 06-621, PICT 05-33225, PICT 05-32906, PICT 05-32439, PAE 22771]
- UNLP [11/X532, 11/1129]
- CONICET [PIP112-200801-00362]
Titanium is a corrosion-resistant and biocompatible material widely used in medical and dental implants. Titanium surfaces, however, are prone to bacterial colonization that could lead to infection, inflammation, and finally to implant failure. Silver nanoparticles (AgNPs) have demonstrated an excellent performance as biocides, and thus their integration to titanium surfaces is an attractive strategy to decrease the risk of implant failure. In this work a simple and efficient method is described to modify Ti/TiO2 surfaces with citrate-capped AgNPs. These nanoparticles spontaneously adsorb on Ti/TiO2, forming nanometer-sized aggregates consisting of individual AgNPs that homogeneously cover the surface. The modified AgNP-Ti/TiO2 surface exhibits a good resistance to colonization by Pseudomonas aeruginosa, a model system for biofilm formation. (C) 2010 Elsevier Inc. All rights reserved.
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