期刊
JOURNAL OF COLLOID AND INTERFACE SCIENCE
卷 332, 期 1, 页码 201-207出版社
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.jcis.2008.12.038
关键词
Antimicrobial agents; Gemini; Surfactants; Bacteriostatic; Semi-fluorinated surfactants; Surfactant monomers
资金
- Ministry of Research of France
Introduction of biocide monomers during the process of polymerization is one of promising approaches in the development of new permanent non leaching biocide materials. In this perspective, new polymerizable semi-fluorinated gemini surfactants, with quaternary ammonium groups as polar heads and an acrylic function as the polymerizable moiety, were synthesized and tested to evaluate their surface active properties alongside with their antibacterial and antifungal properties. Four microbial strains, known for their implication in nosocomial infections, were used to perform the study: Pseudomonas aeruginosa, Staphylococcus aureus, Candida albicans and Aspergillus niger. The biocide efficacy measured by bacterial and fungal growth inhibition expressed as MIC (minimal inhibitory concentration) and MLC (minimal lethal concentration) values was discussed as a function of molecular parameters. As compared to homologue compounds without acrylic part, this study shows that even the introduction of a polymerizable moiety allows to keep remarkable both surfactant and bacteriostatic activities, and allows us to envisage the use of these surfactant monomers to build tip advanced biocide materials. Moreover, semi-fluorinated gemini surfactant monomers with an amide connector came out as broad spectrum biocides (against Grain positive anti negative bacteria and fungi). (C) 2008 Elsevier Inc. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据