Double integration band of HTLV-1 in a young patient with infective dermatitis who developed an acute form of adult T-cell leukemia/lymphoma

Few cases of acute adult T-cell leukemia/lymphoma (ATL) have been diagnosed in young patients. This report is the first to describe a young girl with infective dermatitis associated with HTLV-1 that progressed to acute ATL with Southern blot hybridization and gamma-TCR-rearrangement revealing a monoclonal pattern with two copies of the provirus. (C) 2012 Elsevier B. V. All rights reserved.