期刊
JOURNAL OF CLINICAL VIROLOGY
卷 52, 期 -, 页码 S77-S82出版社
ELSEVIER
DOI: 10.1016/j.jcv.2011.09.015
关键词
HIV-1; HIV viral load; Lower limit of detection; Lower limit of quantification; Real-time PCR
类别
Significant advancements in molecular diagnostics have been made since the inception and application of PCR-based technologies in clinical diagnostic laboratories and the management of HIV-1 infected patients. More recently, real-time PCR has improved the overall performance of assays used for detecting and quantifying HIV-1 RNA viral load in patients undergoing antiretroviral treatment. The effects of these changes and the interpretations of the HIV-1 viral load results are discussed in this review in the context of the different assays used, the viral dynamics of the HIV-1 virus, and the recent changes to HIV-1 treatment guidelines. (C) 2011 Elsevier B.V. All rights reserved.
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