期刊
JOURNAL OF CLINICAL VIROLOGY
卷 51, 期 3, 页码 155-159出版社
ELSEVIER
DOI: 10.1016/j.jcv.2011.04.013
关键词
Influenza virus; HLA-G; Proteases-activated receptors; Inflammation; Host-virus relation; Therapeutic
类别
Influenza is one of the most common infectious diseases in humans occurring as seasonal epidemic and sporadic pandemic outbreaks. The ongoing infections of humans with avian H5N1 influenza A viruses (IAV) and the past 2009 pandemic caused by the quadruple human/avian/swine reassortant (H1N1) virus highlights the permanent threat caused by these viruses. This review aims to describe the interaction between the virus and the host, with a particular focus on the role of proteases and HLA-G in the pathogenicity of influenza viruses. (C) 2011 Elsevier B.V. All rights reserved.
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