期刊
JOURNAL OF CLINICAL PSYCHIATRY
卷 73, 期 7, 页码 941-950出版社
PHYSICIANS POSTGRADUATE PRESS
DOI: 10.4088/JCP.11m07529
关键词
-
资金
- Elminda
- Janssen
- McNeil
- Shire
- Fundacion Dr Manuel Camelo A.C. in Monterrey, Mexico
- Abbott
- Alza
- AstraZeneca
- Boston University
- Bristol-Myers Squibb
- Celltech
- Cephalon
- Eli Lilly
- Esai
- Fundacion Areces (Spain)
- Forest
- Glaxo
- Gliatech
- Hastings Center
- Medice Pharmaceuticals (Germany)
- Merck
- MMC Pediatric
- National Alliance for Research on Schizophrenia and Depression
- National Institute on Drug Abuse
- National Institute of Child Health and Human Development
- National Institute of Mental Health
- Novartis
- Noven
- Neurosearch
- Organon
- Otsuka
- Pfizer
- Pharmacia
- Phase V Communications
- Physicians Academy
- Prechter Foundation
- Quantia Communications
- Reed Exhibitions
- Spanish Child Psychiatry Association
- Stanley Foundation
- UCB Pharma
- Veritas
- Wyeth
- Alcobra
- National Institutes of Health
- Lilly Foundation
- Pediatric Psychopharmacology Council Fund of the Massachusetts General Hospital, Boston
- New River
Objective: To estimate the risks for psychopathology and functional impairments in adulthood among a longitudinal sample of youth with and without attention-deficit/hyperactivity disorder (ADHD) diagnosed in childhood. Method: This was a case-controlled, 16-year (15-19 years) prospective follow-up study of ADHD. 140 boys with and 120 without DSM-III-R ADHD were recruited from pediatric and psychiatric settings. The main outcome measures were structured diagnostic interviews and measures of psychosocial, educational, and neuropsychological functioning. Data were collected from 1988 to 2006. Results: At the 16-year follow-up, subjects with ADHD continued to significantly differ from controls in lifetime rates of antisocial, mood, anxiety, and addictive disorders, but with the exception of a higher interval prevalence of anxiety disorders (20% vs 8%; z = 2.32, P = .02) and smoking dependence (27% vs 11%; z = 2.30, P = .02), the incidence of individual disorders in the 6-year interval between the current and prior follow-up did not differ significantly from controls. At follow-up, the ADHD subjects compared with controls were significantly (P < .05) more impaired in psychosocial, educational, and neuropsychological functioning, differences that could not be accounted for by other active psychopathology. Conclusions: These long-term prospective findings provide further evidence for the high morbidity associated with ADHD across the life cycle, stressing the importance of early recognition of this disorder for prevention and early intervention strategies. These findings also indicate that, in adulthood, ADHD confers significant risks for impairment that cannot be accounted for by other psychopathology. J Clin Psychiatry 2012;73(7):941-950 (c) Copyright 2012 Physicians Postgraduate Press, Inc.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据