期刊
JOURNAL OF CLINICAL PERIODONTOLOGY
卷 39, 期 4, 页码 350-356出版社
WILEY-BLACKWELL
DOI: 10.1111/j.1600-051X.2012.01852.x
关键词
25-hydroxyvitamin D; case-control study; Chinese subjects; chronic obstructive pulmonary disease; periodontitis
资金
- National Natural Science Foundation of China [30872878, 81000449]
- Beijing Science and Technology Program Fund [Z101107050210031]
Aim: To evaluate the associations of serum 25-Hydroxyvitamin D [ 25(OH) D] levels with periodontal health and chronic obstructive pulmonary disease (COPD). Material and Methods: We conducted a case-control study of 193 COPD patients and 181 controls. Their periodontal status and lung function were examined, and serum 25(OH) D levels were measured. Results: Mean serum 25(OH) D concentrations were significantly lower in the COPD group than in the controls (32.1 versus 35.8 nmol/ l; p = 0.002). Serum 25(OH) D concentrations were positively correlated with lung function among non-smokers and negatively correlated with plaque index (PLI) among former smokers. After adjustment for age, gender, body mass index, season and smoking status, periodontal indexes were significantly associated with serum 25(OH) D concentrations (number of remaining teeth among all groups; probing depth, clinical attachment level, bleeding index, PLI and alveolar bone loss among COPD group). Lower serum 25(OH) D concentrations were significantly associated with an increased risk of COPD among former smokers (Odd ratio 4.11; 95% confidence interval 1.47-11.5; p = 0.007) after adjustment for periodontal indexes and other variables. Conclusions: Lower serum 25(OH) D concentrations were significantly associated with poor periodontal health and an increased risk of COPD.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据