期刊
JOURNAL OF CLINICAL PERIODONTOLOGY
卷 39, 期 12, 页码 1183-1190出版社
WILEY
DOI: 10.1111/jcpe.12022
关键词
bone loss; clinical evaluation; implant surface roughness; microbiology; osteoprotegerin; RANKL; turned; TiUnite (R)
资金
- Nobel Biocare AB, Gothenburg, Sweden [2003-144]
Aim This 3-year prospective randomized controlled trial compared the clinical, microbiological and biochemical outcome of minimally (Turned, Tur) and moderately rough (TiUnite (R), TiU) implant surfaces in a split-mouth design. Material and methods The study population included 14 subjects: nine fully edentulous and five partially edentulous subjects with a history of periodontitis. Implants (n = 78, 39 Tur and 39 TiU) were installed randomly in each patient. Peri-implant clinical parameters and intra-oral radiographs were recorded after 3 years of loading. Subgingival plaque and peri-implant crevicular fluid samples were collected and analysed using culture and quantitative polymerase chain reaction for the biofilm, and enzyme-linked immunosorbent assay for the concentration of osteoprotegerin and receptor activator of nuclear factor kappa-B ligand, respectively. Results No statistically significant differences in clinical, microbiological and biochemical parameters could be observed when comparing the Tur and TiU implant surfaces. Conclusion After 3 years of loading, in periodontitis susceptible patients, the moderately rough, TiU implants demonstrated a similar clinical outcome compared with the smoother, turned implants. Longer follow-up and studies using different implant types are needed to confirm the statement that minimally and moderately rough implant surfaces perform similar, both from a clinical and from a microbiological point of view.
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