期刊
JOURNAL OF CLINICAL PERIODONTOLOGY
卷 37, 期 5, 页码 474-485出版社
WILEY
DOI: 10.1111/j.1600-051X.2010.01551.x
关键词
animal study; chronic-type defect; guided bone regeneration; hydrophilicity; implant surfaces
资金
- ITI Foundation [5282007]
- Institute Straumann AG, Basel, Switzerland
P>Objectives The aim of the present study was to evaluate the impact of guided bone regeneration and defect dimension on wound healing at chemically modified titanium implant surfaces (modSLA). Materials and Methods ModSLA implants were placed at chronic-type lateral ridge defects of different heights (H1-H4: 2, 4, 6 and 8 mm) and randomly allocated to either (a) GBR (polyethylene glycol membrane + biphasic calcium phosphate) or (b) untreated control. At 2 and 8 weeks (n=6 dogs each), dissected blocks were processed for histomorphometrical analysis [e.g., percentage linear fill (PLF), regenerated area (RA)]. Results At 8 weeks, both groups revealed comparable mean PLF (%) [Control: H1 (26.1 +/- 5.8)-H4 (60.4 +/- 11.8); GBR: H1 (8.3 +/- 5.3)-H4 (50.7 +/- 23.1)] and RA (mm2) [Control: H1 (2.5 +/- 0.4)-H4 (7.4 +/- 4.1); GBR: H1 (1.8 +/- 1.0)-H4 (10.8 +/- 5.9)] values. A significant difference was observed for the mean PLF values at H1 defects. Conclusion It was concluded that (i) modSLA titanium implants supported bone regeneration and osseointegration at H1-H4 defects and (ii) the present GBR procedure did not seem to improve the outcome of vertical bone regeneration, but tended to increase the mean RA values.
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