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Ji-Youn Han et al.
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JF Gagnon et al.
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Haplotypes of variants in the UDP-glucuronosyltransferase 1A9 and 1A1 genes
F Innocenti et al.
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E Rouits et al.
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Identification of common polymorphisms in the promoter of the UGT1A9 gene: evidence that UGT1A9 protein and activity levels are strongly genetically controlled in the liver
H Girard et al.
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Glucuronidation as a mechanism of intrinsic drug resistance in colon cancer cells: contribution of drug transport proteins
J Cummings et al.
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A novel polymorphism in the promoter region of human UGT1A9 gene (UGT1A9*22) and its effects on the transcriptional activity
H Yamanaka et al.
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Metastatic colorectal cancer: integrating irinotecan into combination and sequential chemotherapy
JY Douillard et al.
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Haplotype structure of the UDP-glucuronosyltransferase 1A1 promoter in different ethnic groups
F Innocenti et al.
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Common human UGT1A polymorphisms and the altered metabolism of irinotecan active metabolite 7-ethyl-10-hydroxycamptothecin (SN-38)
JF Gagné et al.
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M Ando et al.
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Enhanced clearance of topoisomerase I inhibitors from human colon cancer cells by glucuronidation
J Cummings et al.
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Structural heterogeneity at the UDP-glucuronosyltransferase 1 locus:: functional consequences of three novel missense mutations in the human UGT1A7 gene
C Guillemette et al.
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