期刊
JOURNAL OF CLINICAL NEUROSCIENCE
卷 17, 期 9, 页码 1204-1206出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.jocn.2010.01.010
关键词
Anti-NMDA-receptor encephalitis; Encephalitis lethargica; NMDAR antibodies; Paraneoplastic syndrome
Two cases initially diagnosed as encephalitis lethargica are discussed. Both cases satisfied the published diagnostic criteria for encephalitis lethargica, with neuropsychiatric features including complex movement disorder, hypoventilation and altered conscious state. On later investigation N-methyl-D-aspartate receptor antibodies were detected in both cases. With the recent descriptions of tumour related antibodies to neuronal surface antigens in NMDA-receptor encephalitis, we highlight the importance of revisiting a diagnosis which may have prognostic significance. (C) 2010 Elsevier Ltd. All rights reserved.
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