Statin use and the risk of Parkinson disease: a nested case control study

Using the British Columbia Linked Health Databases, we explored the association between the use of statin drugs and the risk of developind Parkinson disease (PD). We followed a cohort of older adults in the Province of British Columbia from 1997 to 2003. Using a study design of nested case control (case-control study within a cohort), the relative risk of developing PD for statin users was 0.94 (0.82-1.09). Our study did not show a statistically significant effect on the risk of PD with statin use. (C) 2008 Elsevier Ltd. All rights reserved.