期刊
JOURNAL OF CLINICAL MICROBIOLOGY
卷 53, 期 1, 页码 319-322出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/JCM.02301-14
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- National Center for Research Resources
- National Center for Advancing Translational Sciences (NCATS) of the National Institutes of Health [1UL1TR001079]
(1-3)-beta-D-Glucan (BDG) from cerebrospinal fluid (CSF) is a promising marker for diagnostic and prognostic aid of central nervous system (CNS) fungal infection, but its relationship to serum values has not been studied. Herein, we detected BDG from CSF at levels 2-fold lower than those in serum in patients without evidence of fungal disease but 25-fold higher than those in in serum in noncryptococcal CNS fungal infections. CSF BDG may be a useful biomarker in the evaluation of fungal CNS disease.
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