期刊
JOURNAL OF CLINICAL MICROBIOLOGY
卷 52, 期 8, 页码 3114-3117出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/JCM.00615-14
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- FIC NIH HHS [R25 TW009337] Funding Source: Medline
- NIAID NIH HHS [R56 AI091827] Funding Source: Medline
Whole-genome sequencing was used to compare longitudinal isolates of Staphylococcus aureus that developed resistance to oxacillin (MIC up to 16 mu g/ml). The mecA gene was absent. A novel 5-bp TATCC frameshift insertion in a gene encoding an ABC transporter similar to that of the teichoic acid translocation ATP-binding protein TagH and a 3-bp GCT nonframeshift insertion in the pdhA pyruvate dehydrogenase gene were detected in the oxacillin-resistant isolates.
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