期刊
JOURNAL OF CLINICAL MICROBIOLOGY
卷 51, 期 12, 页码 4262-4265出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/JCM.02227-13
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- NIAID NIH HHS [T32 AI007140] Funding Source: Medline
Next-generation DNA sequencing can be used to catalog individual organisms within complex, polymicrobial specimens. Here, we utilized deep sequencing of 16S rRNA to implicate Actinomadura madurae as the cause of mycetoma in a diabetic patient when culture and conventional molecular methods were overwhelmed by overgrowth of other organisms.
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