4.7 Article

Phylogenetic Analysis of Non-O157 Shiga Toxin-Producing Escherichia coli Strains by Whole-Genome Sequencing

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JOURNAL OF CLINICAL MICROBIOLOGY
卷 50, 期 12, 页码 4123-4127

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AMER SOC MICROBIOLOGY
DOI: 10.1128/JCM.02262-12

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  1. Joint Institute for Food Safety and Applied Nutrition (JIFSAN), University of Maryland, College Park, MD

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Non-O157 Shiga toxin-producing Escherichia coli (STEC) strains are emerging food-borne pathogens causing life-threatening diseases and food-borne outbreaks. A better understanding of their evolution provides a framework for developing tools to control food safety. We obtained 15 genomes of non-O157 STEC strains, including O26, O111, and O103 strains. Phylogenetic trees revealed a close relationship between O26:H11 and O111:H11 and a scattered distribution of O111. We hypothesize that STEC serotypes with the same H antigens might share common ancestors.

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