4.7 Article

Comparison of Two Molecular Methods for Rapid Diagnosis of Extrapulmonary Tuberculosis

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JOURNAL OF CLINICAL MICROBIOLOGY
卷 49, 期 8, 页码 3065-3067

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AMER SOC MICROBIOLOGY
DOI: 10.1128/JCM.00491-11

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  1. Spanish Ministry of Health and Consumer Affairs
  2. Instituto de Salud Carlos III-ERDF
  3. Spanish Network for Research into Infectious Diseases [REIPI RD06/0008]

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Application of real-time PCR for the detection of Mycobacterium tuberculosis enables results to be obtained in about 2 h. A total of 340 nonrespiratory samples were processed using two real-time PCR assay kits: Xpert MTB/RIF and Cobas TaqMan MTB. The sensitivity and specificity of the Xpert assay were 95% and 100%, respectively, compared to 78% and 98% for the Cobas assay.

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