期刊
JOURNAL OF CLINICAL MICROBIOLOGY
卷 50, 期 1, 页码 142-144出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/JCM.05177-11
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资金
- NIHR Biomedical Research Centre, Oxford, United Kingdom
- Optimer Pharmaceuticals
- bioMerieux
- Optimer
- Novacta
- Pfizer
- Summit
- Medicines Company
- Viropharma
- National Institutes of Health Research (NIHR) [DRF-2010-03-40] Funding Source: National Institutes of Health Research (NIHR)
- National Institute for Health Research [DRF-2010-03-40, NF-SI-0508-10279] Funding Source: researchfish
Isolates from consecutive Clostridium difficile infection (CDI) fecal samples underwent multilocus sequence typing. Potential reinfections with different genotypes were identified in 88/560 (16%) sample pairs taken 1 to 1,414 days (median, 24; interquartile range [IQR], 1 to 52 days) apart; odds of reinfection increased by 58% for every doubling of time between samples. Of 109 sample pairs taken on the same day, 3 (3%) had different genotypes. Considering samples 0 to 7 days apart as the same CDI, 7% of cases had mixed infections with > 1 genotype.
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