4.7 Article

Evaluation of a Loop-Mediated Isothermal Amplification Method Using Fecal Specimens for Differential Detection of Taenia Species from Humans

期刊

JOURNAL OF CLINICAL MICROBIOLOGY
卷 48, 期 9, 页码 3350-3352

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AMER SOC MICROBIOLOGY
DOI: 10.1128/JCM.00697-10

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资金

  1. Japan Society for the Promotion of Science (JSPS) [17256002]
  2. JSPS Asia/Africa Science Platform Fund
  3. JSPS Japan-China Medical Exchange Program
  4. Japan-China Medical Association Fund
  5. Grants-in-Aid for Scientific Research [17256002] Funding Source: KAKEN

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We compared the performance of loop-mediated isothermal amplification (LAMP) with that of a multiplex PCR method for differential detection of human Taenia parasites in fecal specimens from taeniasis patients. The LAMP method, with no false positives, showed a higher sensitivity (88.4%) than the multiplex PCR (37.2%). Thus, it is expected that the LAMP method has a high value for molecular diagnosis of taeniasis.

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