4.7 Article

Evaluation of a Commercial Microarray System for Detection of SHV-, TEM-, CTX-M-, and KPC-Type β-Lactamase Genes in Gram-Negative Isolates

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JOURNAL OF CLINICAL MICROBIOLOGY
卷 48, 期 7, 页码 2618-2622

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AMER SOC MICROBIOLOGY
DOI: 10.1128/JCM.00568-10

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  1. Veterans Affairs
  2. National Institutes of Health [RO3-AI081036]
  3. Geriatric Research Education and Clinical Center [VISN 10]

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We evaluated the ability of a commercial microarray system (Check KPC/ESBL; Check-Points Health BV) to detect clinically important class A beta-lactamase genes. A total of 106 Gram-negative strains were tested. The following sensitivity and specificity results were recorded, respectively: for bla(SHV), 98.8% and 100%; for bla(TEM), 100% and 96.4%; and for bla(CTX-M) and bla(KPC), 100% and 100%.

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