4.7 Article

Accurate and Sensitive Detection of Plasmodium Species in Humans by Use of the Dihydrofolate Reductase-Thymidylate Synthase Linker Region

期刊

JOURNAL OF CLINICAL MICROBIOLOGY
卷 48, 期 10, 页码 3735-3737

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AMER SOC MICROBIOLOGY
DOI: 10.1128/JCM.00898-10

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资金

  1. Wellcome Trust of Great Britain
  2. Wellcome Trust [080867/Z/06/Z]
  3. Thailand Research Fund (TRF)
  4. Commission on Higher Education
  5. Wellcome Trust [080867/Z/06/Z] Funding Source: Wellcome Trust

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A nested-PCR protocol based on the linker region of the Plasmodium dihydrofolate reductase-thymidylate synthase gene (dhfr-ts) was developed. This provides highly sensitive specific detection and identification of the five parasite species that infect humans.

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