相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Oncogenic BRAF Regulates Oxidative Metabolism via PGC1α and MITF
Rizwan Haq et al.
CANCER CELL (2013)
Melanoma adapts to RAF/MEK inhibitors through FOXD3-mediated upregulation of ERBB3
Ethan V. Abel et al.
JOURNAL OF CLINICAL INVESTIGATION (2013)
BCL2A1 is a lineage-specific antiapoptotic melanoma oncogene that confers resistance to BRAF inhibition
Rizwan Haq et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
A Correction to the Perspective Titled: "Phosphoinositides as Regulators of Protein-Chromatin Interactions" by K. Viiri, M. Maki, O. Lohi
Science Signaling (2013)
Guidelines for the use and interpretation of assays for monitoring autophagy
Daniel J. Klionsky et al.
AUTOPHAGY (2012)
Punctate LC3B Expression Is a Common Feature of Solid Tumors and Associated with Proliferation, Metastasis, and Poor Outcome
Rossitza Lazova et al.
CLINICAL CANCER RESEARCH (2012)
ER stress-mediated autophagy promotes Myc-dependent transformation and tumor growth
Lori S. Hart et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
Marked, Homogeneous, and Early [18F]Fluorodeoxyglucose-Positron Emission Tomography Responses to Vemurafenib in BRAF-Mutant Advanced Melanoma
Grant A. McArthur et al.
JOURNAL OF CLINICAL ONCOLOGY (2012)
Discovery of 7-Methyl-5-(1-{[3-(trifluoromethyl)phenyl]acetyl}-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (GSK2606414), a Potent and Selective First-in-Class Inhibitor of Protein Kinase R (PKR)-like Endoplasmic Reticulum Kinase (PERK)
Jeffrey M. Axten et al.
JOURNAL OF MEDICINAL CHEMISTRY (2012)
Dabrafenib in BRAF-mutated metastatic melanoma: a multicentre, open-label, phase 3 randomised controlled trial
Axel Hauschild et al.
LANCET (2012)
Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion
Ravid Straussman et al.
NATURE (2012)
Combined BRAF and MEK Inhibition in Melanoma with BRAF V600 Mutations
Keith T. Flaherty et al.
NEW ENGLAND JOURNAL OF MEDICINE (2012)
Survival in BRAF V600-Mutant Advanced Melanoma Treated with Vemurafenib
Jeffrey A. Sosman et al.
NEW ENGLAND JOURNAL OF MEDICINE (2012)
Role and therapeutic potential of PI3K-mTOR signaling in de novo resistance to BRAF inhibition
W. Deng et al.
PIGMENT CELL & MELANOMA RESEARCH (2012)
Autophagy inhibitor Lys05 has single-agent antitumor activity and reproduces the phenotype of a genetic autophagy deficiency
Quentin McAfee et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Beyond the endoplasmic reticulum: atypical GRP78 in cell viability, signalling and therapeutic targeting
Min Ni et al.
BIOCHEMICAL JOURNAL (2011)
Resistance to BRAF Inhibitors: Unraveling Mechanisms and Future Treatment Options
Jessie Villanueva et al.
CANCER RESEARCH (2011)
Measurements of Tumor Cell Autophagy Predict Invasiveness, Resistance to Chemotherapy, and Survival in Melanoma
Xiao-Hong Ma et al.
CLINICAL CANCER RESEARCH (2011)
Principles and Current Strategies for Targeting Autophagy for Cancer Treatment
Ravi K. Amaravadi et al.
CLINICAL CANCER RESEARCH (2011)
RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF(V600E)
Poulikos I. Poulikakos et al.
NATURE (2011)
Improved Survival with Vemurafenib in Melanoma with BRAF V600E Mutation
Paul B. Chapman et al.
NEW ENGLAND JOURNAL OF MEDICINE (2011)
Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy
Daniel F. Egan et al.
SCIENCE (2011)
The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation
Peter Walter et al.
SCIENCE (2011)
Acquired Resistance to BRAF Inhibitors Mediated by a RAF Kinase Switch in Melanoma Can Be Overcome by Cotargeting MEK and IGF-1R/PI3K
Jessie Villanueva et al.
CANCER CELL (2010)
The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5
Kasper M. A. Rouschop et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
Autophagy in cutaneous malignant melanoma
Rossitza Lazova et al.
JOURNAL OF CUTANEOUS PATHOLOGY (2010)
COT drives resistance to RAF inhibition through MAP kinase pathway reactivation
Cory M. Johannessen et al.
NATURE (2010)
Melanomas acquire resistance toB-RAF(V600E) inhibition by RTK or N-RAS upregulation
Ramin Nazarian et al.
NATURE (2010)
Inhibition of Mutated, Activated BRAF in Metastatic Melanoma
Keith T. Flaherty et al.
NEW ENGLAND JOURNAL OF MEDICINE (2010)
Regulation of autophagy by ATF4 in response to severe hypoxia
T. Rzymski et al.
ONCOGENE (2010)
Akt and Autophagy Cooperate to Promote Survival of Drug-Resistant Glioma
Qi-Wen Fan et al.
SCIENCE SIGNALING (2010)
ULK-Atg13-FIP200 Complexes Mediate mTOR Signaling to the Autophagy Machinery
Chang Hwa Jung et al.
MOLECULAR BIOLOGY OF THE CELL (2009)
Oncogenic B-RAF Negatively Regulates the Tumor Suppressor LKB1 to Promote Melanoma Cell Proliferation
Bin Zheng et al.
MOLECULAR CELL (2009)
Uncoupling of the LKB1-AMPKα Energy Sensor Pathway by Growth Factors and Oncogenic BRAFV600E
Rosaura Esteve-Puig et al.
PLOS ONE (2009)
Akt inhibition promotes autophagy and sensitizes PTEN-null tumors to lysosomotropic agents
Michael Degtyarev et al.
JOURNAL OF CELL BIOLOGY (2008)
JNK1-mediated phosphorylation of BcI-2 regulates starvation-induced autophagy
Yongjie Wei et al.
MOLECULAR CELL (2008)
Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities
Inki Kim et al.
NATURE REVIEWS DRUG DISCOVERY (2008)
The roles of therapy-induced autophagy and necrosis in cancer treatment
Ravi K. Amaravadi et al.
CLINICAL CANCER RESEARCH (2007)
Selective autophagy of the endoplasmic reticulum
Sebastian Bernales et al.
AUTOPHAGY (2007)
Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma
Ravi K. Amaravadi et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Direct observation of individual endogenous protein complexes in situ by proximity ligation
Ola Soderberg et al.
NATURE METHODS (2006)
Endoplasmic reticulum stress triggers autophagy
Tomohiro Yorimitsu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Autophagy - An ER protein quality control process
Kristina B. Kruse et al.
AUTOPHAGY (2006)
Clonogenic assay of cells in vitro
Nicolaas A. P. Franken et al.
NATURE PROTOCOLS (2006)
Autophagy in metazoans: Cell survival in the land of plenty
JJ Lum et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2005)
Role of autophagy in temozolomide-induced cytotoxicity for malignant glioma cells
T Kanzawa et al.
CELL DEATH AND DIFFERENTIATION (2004)
Activating transcription factor 3 is integral to the eukaryotic initiation factor 2 kinase stress response
HY Jiang et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
LC3 conjugation system in mammalian autophagy
I Tanida et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2004)
Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response
A Bertolotti et al.
NATURE CELL BIOLOGY (2000)