期刊
JOURNAL OF CLINICAL INVESTIGATION
卷 122, 期 7, 页码 2337-2343出版社
AMER SOC CLINICAL INVESTIGATION INC
DOI: 10.1172/JCI60434
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资金
- NCI NIH HHS [R01 CA103846] Funding Source: Medline
Zebrafish have been widely used as a model system for studying developmental processes, but in the last decade, they have also emerged as a valuable system for modeling human disease. The development and function of zebrafish organs are strikingly similar to those of humans, and the ease of creating mutant or transgenic fish has facilitated the generation of disease models. Here, we highlight the use of zebrafish for defining disease pathways and for discovering new therapies.
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