期刊
JOURNAL OF CLINICAL INVESTIGATION
卷 121, 期 6, 页码 2111-2117出版社
AMER SOC CLINICAL INVESTIGATION INC
DOI: 10.1172/JCI57132
关键词
-
资金
- Merck Co.
- Life Sciences Institute of the University of Michigan
- NIH National Institute of Diabetes and Digestive and Kidney Diseases [R01DK090262, K08DK078851, R01DK060591]
The obesity epidemic has forced us to evaluate the role of inflammation in the health complications of obesity. This has led to a convergence of the fields of immunology and nutrient physiology and the understanding that they are inextricably linked. The reframing of obesity as an inflammatory condition has had a wide impact on our conceptualization of obesity-associated diseases. In this Review, we highlight the cellular and molecular mechanisms at play in the generation of obesity-induced inflammation. We also emphasize how defining the immune regulation in metabolic tissues has broadened the understanding of the diversity of inflammatory responses.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据