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Jennifer O'Neil et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2007)
HIF-2α promotes hypoxic cell proliferation by enhancing c-Myc transcriptional activity
John D. Gordan et al.
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The hypoxia-inducible factor 2α N-terminal and C-terminal transactivation domains cooperate to promote renal tumorigenesis in vivo
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Notch signalling limits angiogenic cell behaviour in developing zebrafish arteries
Arndt F. Siekmann et al.
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Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis
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Notch2, but not Notch1, is required for proximal fate acquisition in the mammalian nephron
Hui-Teng Cheng et al.
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Sorafenib in advanced clear-cell renal-cell carcinoma
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Renal cancer cells lacking hypoxia inducible factor (HIF)-1 alpha expression maintain vascular endothelial growth factor expression through HIF-2 alpha
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Blockade of Dll4 inhibits tumour growth by promoting non-productive angiogenesis
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Inhibition of Dll4 signalling inhibits tumour growth by deregulating angiogenesis
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Notch signaling in cancer
Lucio Miele et al.
CURRENT MOLECULAR MEDICINE (2006)
Notch pathway inhibition depletes stem-like cells and blocks engraftment in embryonal brain tumors
Xing Fan et al.
CANCER RESEARCH (2006)
Myc is a Notch1 transcriptional target and a requisite for Notch1-induced mammary tumorigenesis in mice
Apostolos Klinakis et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Notch controls proliferation and differentiation of stem cells in a dose-dependent manner
M Guentchev et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2006)
被撤回的出版物: Down-regulation of Notch-1 contributes to cell growth inhibition and apoptosis in pancreatic cancer cells (Retracted article. See vol. 17, pg. 2268, 2018)
ZW Wang et al.
MOLECULAR CANCER THERAPEUTICS (2006)
Genetic and epigenetic analysis of von Hippel-Lindau (VHL) gene alterations and relationship with clinical variables in sporadic renal cancer
RE Banks et al.
CANCER RESEARCH (2006)
The Notch pathway in cancer:: Differentiation gone awry
J Sjölund et al.
EUROPEAN JOURNAL OF CANCER (2005)
Hypoxia requires Notch signaling to maintain the undifferentiated cell state
MV Gustafsson et al.
DEVELOPMENTAL CELL (2005)
Up-regulation of delta-like 4 ligand in human tumor vasculature and the role of basal expression in endothelial cell function
NS Patel et al.
CANCER RESEARCH (2005)
Suppression of p53 by Notch in lymphomagenesis: Implications for initiation and regression
LJ Beverly et al.
CANCER RESEARCH (2005)
Hypoxia-induced dedifferentiation of tumor cells -: A mechanism behind heterogeneity and aggressiveness of solid tumors
H Axelson et al.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2005)
Notch1 modulates timing of G1-S progression by inducing SKP2 transcription and p27Kip1 degradation
LM Sarmento et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
Crosstalk between tumor and endothelial cells promotes tumor angiogenesis by MAPK activation of Notch signaling
QH Zeng et al.
CANCER CELL (2005)
Contrasting properties of hypoxia-inducible factor 1 (HIF-1) and HIF-2 in von Hippel-Lindau-associated renal cell carcinoma
RR Raval et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
Notch signals control the fate of immature progenitor cells in the intestine
S Fre et al.
NATURE (2005)
Notch/γ-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells
JH van Es et al.
NATURE (2005)
Effects of the histone deacetylase inhibitor valproic acid on Notch signalling in human neuroblastoma cells
MT Stockhausen et al.
BRITISH JOURNAL OF CANCER (2005)
Notch signaling in development and disease
EM Hansson et al.
SEMINARS IN CANCER BIOLOGY (2004)
Intramembrane proteotysis: Theme and variations
MS Wolfe et al.
SCIENCE (2004)
Role of VHL gene mutation in human cancer
WY Kim et al.
JOURNAL OF CLINICAL ONCOLOGY (2004)
Strict regulation of CAIXG250/MN by HIF-1α in clear cell renal cell carcinoma
K Grabmaier et al.
ONCOGENE (2004)
Biological significance of p27 and Skp2 expression in renal cell carcinoma. A systematic analysis of primary and metastatic tumour tissues using a tissue microarray technique
C Langner et al.
VIRCHOWS ARCHIV (2004)
Modulation of notch processing by γ-secretase inhibitors causes intestinal goblet cell metaplasia and induction of genes known to specify gut secretory lineage differentiation
J Milano et al.
TOXICOLOGICAL SCIENCES (2004)
Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia
AP Weng et al.
SCIENCE (2004)
Recent genetic studies of mouse kidney development
J Yu et al.
CURRENT OPINION IN GENETICS & DEVELOPMENT (2004)
Expression of cyclin D1, D3, E, and p27 in human renal cell carcinoma analysed by tissue microarray
Y Hedberg et al.
BRITISH JOURNAL OF CANCER (2003)
HES and HERP families: Multiple effectors of the Notch signaling pathway
T Iso et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2003)
Hypoxia alters gene expression in human neuroblastoma cells toward an immature and neural crest-like phenotype
A Jögi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
The contribution of VHL substrate binding and HIF1-α to the phenotype of VHL loss in renal cell carcinoma
JK Maranchie et al.
CANCER CELL (2002)
Inhibition of HIF is necessary for tumor suppression by the von Hippel-Lindau protein
K Kondo et al.
CANCER CELL (2002)
Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes
Jo Vandesompele et al.
GENOME BIOLOGY (2002)
FIH-1:: a novel protein that interacts with HIF-1α and VHL to mediate repression of HIF-1 transcriptional activity
PC Mahon et al.
GENES & DEVELOPMENT (2001)
Induction of cyclin D1 transcription and CDK2 activity by Notchic:: Implication for cell cycle disruption in transformation by Notchic
C Ronchini et al.
MOLECULAR AND CELLULAR BIOLOGY (2001)
Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation
A Rangarajan et al.
EMBO JOURNAL (2001)