期刊
JOURNAL OF CLINICAL EPIDEMIOLOGY
卷 64, 期 2, 页码 163-171出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.jclinepi.2010.03.016
关键词
Predictive intervals; Posterior probabilities; Ranking; Network meta-analysis; Mixed-treatment comparison; Bayesian meta-analysis
资金
- European Research Council [260559] Funding Source: Medline
- Medical Research Council [G0800800] Funding Source: Medline
- MRC [G0800800] Funding Source: UKRI
- Medical Research Council [G0800800] Funding Source: researchfish
- European Research Council (ERC) [260559] Funding Source: European Research Council (ERC)
Objective: To present some simple graphical and quantitative ways to assist interpretation and improve presentation of results from multiple-treatment meta-analysis (MTM). Study Design and Setting: We reanalyze a published network of trials comparing various antiplatelet interventions regarding the incidence of serious vascular events using Bayesian approaches for random effects MTM, and we explore the advantages and drawbacks of various traditional and new forms of quantitative displays and graphical presentations of results. Results: We present the results under various forms, conventionally based on the mean of the distribution of the effect sizes; based on predictions; based on ranking probabilities; and finally, based on probabilities to be within an acceptable range from a reference. We show how to obtain and present results on ranking of all treatments and how to appraise the overall ranks. Conclusions: Bayesian methodology offers a multitude of ways to present results from MTM models, as it enables a natural and easy estimation of all measures based on probabilities, ranks, or predictions. (C) 2011 Elsevier Inc. All rights reserved.
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