期刊
JOURNAL OF CLINICAL EPIDEMIOLOGY
卷 63, 期 8, 页码 826-833出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.jclinepi.2009.11.020
关键词
Propensity scores; Classification and regression trees (CART); Recursive partitioning algorithms; Neural networks; Logistic regression; Review
资金
- University of North Carolina at Chapel Hill Center for AIDS Research (CFAR)
- NIH [P30 AI50410]
- UNC-GlaxoSmithKline Center for Excellence in Pharmacoepidemiology and Public Health
- UNC School of Public Health
- NIH/NIAID [5 T32 AI 07001-31]
Objective: Propensity scores for the analysis of observational data are typically estimated using logistic regression. Our objective in this review was to assess machine learning alternatives to logistic regression, which may accomplish the same goals but with fewer assumptions or greater accuracy. Study Design and Setting: We identified alternative methods for propensity score estimation and/or classification from the public health, biostatistics, discrete mathematics, and computer science literature, and evaluated these algorithms for applicability to the problem of propensity score estimation, potential advantages over logistic regression, and ease of use. Results: We identified four techniques as alternatives to logistic regression: neural networks, support vector machines, decision trees (classification and regression trees [CART]), and meta-classifiers (in particular, boosting). Conclusion: Although the assumptions of logistic regression are well understood, those assumptions are frequently ignored. All four alternatives have advantages and disadvantages compared with logistic regression. Boosting. (meta-classifiers) and, to a lesser extent, decision trees (particularly CART), appear to be most promising for use in the context of propensity score analysis, but extensive simulation studies are needed to establish their utility in practice. (C) 2010 Elsevier Inc. All rights reserved.
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