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Mitogen-activated protein kinases in apoptosis regulation
T Wada et al.
ONCOGENE (2004)
Overcoming resistance to γ-rays in squamous carcinoma cells by poly-drug elevation of ceramide levels
G Alphonse et al.
ONCOGENE (2004)
The histone deacetylase inhibitor MS-275 interacts synergistically with fludarabine to induce apoptosis in human leukemia cells
SC Maggio et al.
CANCER RESEARCH (2004)
Rapid shortening of telomere length in response to ceramide involves the inhibition of telomere binding activity of nuclear glyceraldehyde-3-phosphate dehydrogenase
KP Sundararaj et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Cannabinoids inhibit the vascular endothelial growth factor pathway in gliomas
C Blázquez et al.
CANCER RESEARCH (2004)
Pivotal role of the cell death factor BNIP3 in ceramide-induced autophagic cell death in malignant glioma cells
S Daido et al.
CANCER RESEARCH (2004)
Role for mammalian neutral sphingomyelinase 2 in confluence-induced growth arrest of MCF7 cells
N Marchesini et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Ceramide promotes apoptosis in lung cancer-derived A549 cells by a mechanism involving c-Jun NH2-terminal kinase
SM Kurinna et al.
CANCER RESEARCH (2004)
Defects in cell growth regulation by C18:0-ceramide and longevity assurance gene 1 in human head and neck squamous cell carcinomas
S Koybasi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Cisplatin-induced CD95 redistribution into membrane lipid rafts of HT29 human colon cancer cells
S Lacour et al.
CANCER RESEARCH (2004)
Cellular events involved in butyric acid-induced T cell apoptosis
T Kurita-Ochiai et al.
JOURNAL OF IMMUNOLOGY (2003)
Radiation and ceramide-induced apoptosis
R Kolesnick et al.
ONCOGENE (2003)
Ceramide induces cell cycle arrest and upregulates p27kip in nasopharyngeal carcinoma cells
XF Zhu et al.
CANCER LETTERS (2003)
Role of ceramide in mediating apoptosis of irradiated LNCaP prostate cancer cells
K Kimura et al.
CELL DEATH AND DIFFERENTIATION (2003)
Modulators of ceramide metabolism sensitize colorectal cancer cells to chemotherapy: A novel treatment strategy
DA Litvak et al.
JOURNAL OF GASTROINTESTINAL SURGERY (2003)
Ceramide in apoptosis: an overview and current perspectives
BJ Pettus et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2002)
Ceramide signaling in fenretinide-induced endothelial cell apoptosis
A Erdreich-Epstein et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Activation of the Drosophila MLK by ceramide reveals TNF-α and ceramide as agonists of mammalian MLK3
P Sathyanarayana et al.
MOLECULAR CELL (2002)
Caspase-dependent initiation of apoptosis and necrosis by the Fas receptor in lymphoid cells: onset of necrosis is associated with delayed ceramide increase
CA Hetz et al.
JOURNAL OF CELL SCIENCE (2002)
Ceramide and reactive oxygen species generated by H2O2 induce caspase-3-independent degradation of Akt/protein kinase B
D Martín et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Ceramide increases Fas-mediated apoptosis in glioblastoma cells through FLIP down-regulation
G Yoon et al.
JOURNAL OF NEURO-ONCOLOGY (2002)
Increase of ceramide in adriamycin-induced HL-60 cell apoptosis: detection by a novel anti-ceramide antibody
M Kawase et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2002)
Mitochondrial cytochrome c release precedes transmembrane depolarisation and caspase-3 activation during ceramide-induced apoptosis of Jurkat T cells
AC Hearps et al.
APOPTOSIS (2002)
Ceramide induces activation of the mitochondrial/capases pathway in Jurkat and SCC61 cells sensitive to γ-radiation but activation of this sequence is defective in radioresistant SQ20B cells
G Alphonse et al.
INTERNATIONAL JOURNAL OF RADIATION BIOLOGY (2002)
Ceramide induces mitochondrial activation and apoptosis via a Bax-dependent pathway in human carcinoma cells
C von Haefen et al.
ONCOGENE (2002)
N-(4-hydroxyphenyl)retinamide increases ceramide and is cytotoxic to acute lymphoblastic leukemia cell lines, but not to non-malignant lymphocytes
PH O'Donnell et al.
LEUKEMIA (2002)
P53 mediates ceramide-induced apoptosis in SKN-SH cells
SS Kim et al.
ONCOGENE (2002)
Changes in ceramide levels upon catechins-induced apoptosis in LoVo cells
XH Tan et al.
LIFE SCIENCES (2002)
Ceramide-induced inhibition of Akt is mediated through protein kinase Cζ -: Implications for growth arrest
NA Bourbon et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Death-associated protein (DAP) kinase plays a central role in ceramide-induced apoptosis in cultured hippocampal neurons
D Pelled et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
New functions for the matrix metalloproteinases in cancer progression
M Egeblad et al.
NATURE REVIEWS CANCER (2002)
The pro-apoptotic function of death-associated protein kinase is controlled by a unique inhibitory autophosphorylation-based mechanism
G Shohat et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Selective hydrolysis of a mitochondrial pool of sphingomyelin induces apoptosis
H Birbes et al.
FASEB JOURNAL (2001)
FAS activation induces dephosphorylation of SR proteins -: Dependence on the de novo generation of ceramide and activation of protein phosphatase 1
CE Chalfant et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Sphingosine 1-phosphate antagonizes apoptosis of human leukemia cells by inhibiting release of cytochrome c and Smac/DIABLO from mitochondria
O Cuvillier et al.
BLOOD (2001)
Ceramide inhibition of mammalian phospholipase D1 and D2 activities is antagonized by phosphatidylinositol 4,5-bisphosphate
IN Singh et al.
BIOCHEMISTRY (2001)
Bax-dependent apoptosis induced by ceramide in HL-60 cells
HJ Kim et al.
FEBS LETTERS (2001)
Molecular mechanisms of ceramide-mediated telomerase inhibition in the A549 human lung adenocarcinoma cell line
B Ogretmen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Role of ceramide in mediating the inhibition of telomerase activity in A549 human lung adenocarcinoma cells
B Ogretmen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Endonuclease G is an apoptotic DNase when released from mitochondria
LY Li et al.
NATURE (2001)
Taxol-induced ceramide generation and apoptosis in human breast cancer cells
AG Charles et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2001)
Phosphorylation of Bcl2 and regulation of apoptosis
PP Ruvolo et al.
LEUKEMIA (2001)
Role of ceramide during cisplatin-induced apoptosis in C6 glioma cells
S Noda et al.
JOURNAL OF NEURO-ONCOLOGY (2001)
Regulation of cyclin-dependent kinase 2 activity by ceramide
JY Lee et al.
EXPERIMENTAL CELL RESEARCH (2000)
Changes in ceramide and sphingomyelin following fludarabine treatment of human chronic B-cell leukemia cells
SS Biswal et al.
TOXICOLOGY (2000)
Ceramide directly activates protein kinase C ζ to regulate a stress-activated protein kinase signaling complex
NA Bourbon et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Akt mediates insulin rescue from apoptosis in brown adipocytes: effect of ceramide
P Navarro et al.
GROWTH HORMONE & IGF RESEARCH (2000)
Combined cytotoxic action of paclitaxel and ceramide against the human Tu138 head and neck squamous carcinoma cell line
S Mehta et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2000)
Ceramide inhibits protein kinase B/Akt by promoting dephosphorylation of serine 473
KM Schubert et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Serine palmitoyltransferase regulates de novo ceramide generation during etoposide-induced apoptosis
DK Perry et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Role of c-jun expression increased by heat shock- and ceramide-activated caspase-3 in HL-60 cell apoptosis -: Possible involvement of ceramide in heat shock-induced apoptosis
T Kondo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Inhibition of PKB/Akt1 by C2-ceramide involves activation of ceramide-activated protein phosphatase in PC12 cells
M Salinas et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2000)
Ceramide in the eukaryotic stress response
YA Hannun et al.
TRENDS IN CELL BIOLOGY (2000)
Ordering of ceramide formation, caspase activation, and Bax/Bcl-2 expression during etoposide-induced apoptosis in C6 glioma cells
N Sawada et al.
CELL DEATH AND DIFFERENTIATION (2000)
Ceramide induces apoptosis in neuroblastoma cell cultures resistant to CD95 (Fas/APO-1)-mediated apoptosis
JT Schaefer et al.
JOURNAL OF PEDIATRIC SURGERY (2000)
Anti-tumoral action of cannabinoids: Involvement of sustained ceramide accumulation and extracellular signal-regulated kinase activation
I Galve-Roperh et al.
NATURE MEDICINE (2000)
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