期刊
JOURNAL OF CLINICAL AND EXPERIMENTAL NEUROPSYCHOLOGY
卷 30, 期 8, 页码 920-930出版社
TAYLOR & FRANCIS INC
DOI: 10.1080/13803390801888733
关键词
Multiple sclerosis; Executive function; Dysexecutive syndrome; Functional outcomes; Disability
资金
- NINDS NIH HHS [R01 NS043362-01A2] Funding Source: Medline
- NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE [R01NS043362] Funding Source: NIH RePORTER
Although cognitive deficits are common in persons with multiple sclerosis (MS), the relationship between subjective complaints and objective impairment is sometimes obscured. To elaborate this issue, the present study examined the relationship between subjective complaints of dysexecutive syndrome, neuropsychological performance, and self-reported activities of daily living in 42 people with MS and 13 control participants. Regression analyses revealed that subjective complaints of impairment, measured by the Frontal Systems Behavior Scale (FrSBe), emerged as a significant predictor of neuropsychological deficit and poor adaptive function. Accordingly, subjective complaints of dysexecutive function in MS may serve as a potent indicator of cognitive and functional impairment. Implications for research and clinical practice are discussed.
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