Novel molecularly imprinted polymers based on multi-walled carbon nanotubes with binary functional monomer for the solid-phase extraction of erythromycin from chicken muscle

A new surface imprinting technique was reported to synthesize multi-walled carbon nanotubes-molecularly imprinted polymers (MWNTs-MIPs) using erythromycin as the template, acryloyl-beta-cyclodextrin (acryloyl-beta-CD) and methacrylic acid (MM) as the binary functional monomers. The MWNTs-MIPs were characterized by transmission electron microscopy (TEM), scanning electron micrograph (SEM) and Fourier transform-infrared spectroscopy (FT-IR). Adsorption experiments indicated the MWNTs-MIPs prepared with acryloyl-beta-CD and MAA have high selective for erythromycin. The feasibility of the MWNTs-MIPs as solid-phase extraction (SPE) sorbent was evaluated, and the results showed that it can selectively extract erythromycin from chicken muscle samples with the recoveries ranging from 85.3% to 95.8%. The molecularly imprinted solid-phase extraction (MISPE) method could be applied for preconcentration and purification of erythromycin from chicken muscle samples. (C) 2011 Elsevier B.V. All rights reserved.