期刊
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
卷 878, 期 17-18, 页码 1365-1381出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.jchromb.2009.10.030
关键词
Nuclear magnetic resonance spectroscopy; Toxic organophosphorus compounds; Pesticides; Chemical warfare agents; Nerve agents; Chemical Weapons Convention; Enzyme inhibition; Antidotes; Exposure determination; Metabolism; Degradation; Biomedical samples; Environmental samples; Urban matrices
This review presents with selected examples the versatility of nuclear magnetic resonance (NMR) spectroscopy in the analysis of toxic organophosphorus (OP) compounds, i.e. OP pesticides and chemical warfare agents (CWAs). Several NMR applications of biological importance, like studies on inhibition mechanism, metabolism, and exposure determination, are presented. The review also concerns with the environmental analysis of OP compounds by NMR spectroscopy. Residue analysis of environment and food samples as well as characterization of degradation in environment is discussed. Some of the NMR studies that have been done to support the Chemical Weapons Convention, i.e. the development of suitable CWA detoxification means and the method development of verification analysis for CWAs and their degradation products, are outlined. (C) 2009 Elsevier B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据