期刊
出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.jchromb.2008.05.022
关键词
Reviews; LC stationary phases; Chiral stationary phases; Protein; Glycoprotein; Antibody; Chiral separation; Enantioseparation
资金
- Ministry of Education, Culture, Sports, Science and Technology, Japan
Chiral stationary phases (CSPs) based on proteins or glycoproteins have been developed for the enantioseparations of various compounds. In 2001, a review article [J. Haginaka. J. Chromatogr. A, 906 (2001) 253] dealing with CSPs based on proteins and glycoproteins was published. After that serum albumin from other species, penicillin G-acylase, antibodies, fatty acid binding protein and streptavidin were newly introduced as the chiral selectors in CSPs. This review article deals with recent progresses in CSPs based on protein or glycoproteins in LC after 2001, focusing on their enantioselective properties and chiral recognition mechanisms. (c) 2008 Elsevier B.V. All rights reserved.
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