相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Homeostatic Sleep Pressure is the Primary Factor for Activation of Cortical nNOS/NKI Neurons
Lars Dittrich et al.
NEUROPSYCHOPHARMACOLOGY (2015)
Clinical Correlates of Zolpidem-Associated Complex Sleep-Related Behaviors: Age Effect
Cheng-Sheng Chen et al.
JOURNAL OF CLINICAL PSYCHIATRY (2014)
Opposing roles of cotransmission of dynorphin and hypocretin on reward and motivation
Xuan Li et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Hypocretin (orexin) facilitates reward by attenuating the antireward effects of its cotransmitter dynorphin in ventral tegmental area
John W. Muschamp et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Coreleased Orexin and Glutamate Evoke Nonredundant Spike Outputs and Computations in Histamine Neurons
Cornelia Schoene et al.
CELL REPORTS (2014)
Orexin receptor antagonist-induced sleep does not impair the ability to wake in response to emotionally salient acoustic stimuli in dogs
Pamela L. Tannenbaum et al.
FRONTIERS IN BEHAVIORAL NEUROSCIENCE (2014)
Suvorexant for the treatment of insomnia
Laura H. Jacobson et al.
EXPERT REVIEW OF CLINICAL PHARMACOLOGY (2014)
The hypocretin/orexin antagonist almorexant promotes sleep without impairment of performance in rats
Stephen R. Morairty et al.
FRONTIERS IN NEUROSCIENCE (2014)
Social and environmental contexts modulate sleep deprivation-induced c-Fos activation in rats
Samuel Deurveilher et al.
BEHAVIOURAL BRAIN RESEARCH (2013)
A role for cortical nNOS/NK1 neurons in coupling homeostatic sleep drive to EEG slow wave activity
Stephen R. Morairty et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Orexin Receptor Antagonists Differ from Standard Sleep Drugs by Promoting Sleep at Doses That Do Not Disrupt Cognition
Jason M. Uslaner et al.
SCIENCE TRANSLATIONAL MEDICINE (2013)
Human hypocretin and melanin-concentrating hormone levels are linked to emotion and social interaction
Ashley M. Blouin et al.
NATURE COMMUNICATIONS (2013)
Dual orexin receptor antagonists show distinct effects on locomotor performance, ethanol interaction and sleep architecture relative to gamma-aminobutyric acid-A receptor modulators
Andres D. Ramirez et al.
FRONTIERS IN NEUROSCIENCE (2013)
In the Zzz Zone: The Effects of Z-Drugs on Human Performance and Driving
Naren Gunja
JOURNAL OF MEDICAL TOXICOLOGY (2013)
Zolpidem for insomnia
David J. Greenblatt et al.
EXPERT OPINION ON PHARMACOTHERAPY (2012)
Optogenetic Probing of Fast Glutamatergic Transmission from Hypocretin/Orexin to Histamine Neurons In Situ
Cornelia Schoene et al.
JOURNAL OF NEUROSCIENCE (2012)
Orexin receptor antagonism: an ascending multiple-dose study with almorexant
Petra Hoever et al.
JOURNAL OF PSYCHOPHARMACOLOGY (2012)
CONTROL OF SLEEP AND WAKEFULNESS
Ritchie E. Brown et al.
PHYSIOLOGICAL REVIEWS (2012)
Dual Hypocretin Receptor Antagonism Is More Effective for Sleep Promotion than Antagonism of Either Receptor Alone
Stephen R. Morairty et al.
PLOS ONE (2012)
Mechanism for Hypocretin-mediated sleep-to-wake transitions
Matthew E. Carter et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Promotion of Sleep by Suvorexant--A Novel Dual Orexin Receptor Antagonist
Christopher J. Winrow et al.
JOURNAL OF NEUROGENETICS (2011)
Differential Effects of the Dual Orexin Receptor Antagonist Almorexant and the GABAA-α1 Receptor Modulator Zolpidem, Alone or Combined with Ethanol, on Motor Performance in the Rat
Michel A. Steiner et al.
NEUROPSYCHOPHARMACOLOGY (2011)
Effects of eszopiclone and zolpidem on sleep-wake behavior, anxiety-like behavior and contextual memory in rats
Max P. Huang et al.
BEHAVIOURAL BRAIN RESEARCH (2010)
Orexin Receptor Antagonism, a New Sleep-Promoting Paradigm: An Ascending Single-Dose Study With Almorexant
P. Hoever et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2010)
Discovery of the Dual Orexin Receptor Antagonist [(7R)-4-(5-Chloro-1,3-benzoxazol-2-yl)-7-methyl-1,4-diazepan-1-yl][5-methyl-2-(2H-1,2,3-triazol-2-yl)phenyl]methanone (MK-4305) for the Treatment of Insomnia
Christopher D. Cox et al.
JOURNAL OF MEDICINAL CHEMISTRY (2010)
IMMUNOHISTOCHEMICAL EVIDENCE FOR SYNAPTIC RELEASE OF GLUTAMATE FROM OREXIN TERMINALS IN THE LOCUS COERULEUS
P. Henny et al.
NEUROSCIENCE (2010)
Intact learning and memory in rats following treatment with the dual orexin receptor antagonist almorexant
Hendrik Dietrich et al.
PSYCHOPHARMACOLOGY (2010)
c-Fos protein expression is increased in cholinergic neurons of the rodent basal forebrain during spontaneous and induced wakefulness
J. T. McKenna et al.
BRAIN RESEARCH BULLETIN (2009)
Blockade of Orexin-1 Receptors Attenuates Orexin-2 Receptor Antagonism-Induced Sleep Promotion in the Rat
Christine Dugovic et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2009)
Organization of histamine-immunoreactive, tuberomammillary neurons projecting to the dorsal tier of the substantia nigra compacta in the rat
Sat-Byol Lee et al.
BRAIN RESEARCH (2008)
Hypnosedative-Induced Complex Behaviours Incidence, Mechanisms and Management
Christian R. Dolder et al.
CNS DRUGS (2008)
Orexin receptor antagonists: Medicinal chemistry and therapeutic potential
Anthony J. Roecker et al.
CURRENT TOPICS IN MEDICINAL CHEMISTRY (2008)
Selective 5HT(2A) and 5HT(6) receptor antagonists promote sleep in rats
Stephen R. Morairty et al.
SLEEP (2008)
Insomnia: Prevalence, Impact, Pathogenesis, Differential Diagnosis, and Evaluation
Evelyn Mai et al.
SLEEP MEDICINE CLINICS (2008)
The dynamics of neurobehavioural recovery following sleep loss
Nicole Lamond et al.
JOURNAL OF SLEEP RESEARCH (2007)
Promotion of sleep by targeting the orexin system in rats, dogs and humans
Catherine Brisbare-Roch et al.
NATURE MEDICINE (2007)
Differential c-Fos immunoreactlivity in arousal-promoting cell groups following systemic administration of caffeine in rats
Samuel Deurveilher et al.
JOURNAL OF COMPARATIVE NEUROLOGY (2006)
Arousal and reward: a dichotomy in orexin function
Glenda C. Harris et al.
TRENDS IN NEUROSCIENCES (2006)
Afferents to the orexin neurons of the rat brain
K Yoshida et al.
JOURNAL OF COMPARATIVE NEUROLOGY (2006)
Hypnotics and Driving Safety: Meta-Analyses of Randomized Controlled Trials Applying the on-the-Road Driving Test
Joris C. Verster et al.
CURRENT DRUG SAFETY (2006)
Discharge of identified orexin/hypocretin neurons across the sleep-waking cycle
MG Lee et al.
JOURNAL OF NEUROSCIENCE (2005)
Input of orexin/hypocretin by a genetically encoded neurons revealed tracer in mice
T Sakurai et al.
NEURON (2005)
Direct and indirect inhibition by catecholamines of hypocretin/orexin neurons
Y Li et al.
JOURNAL OF NEUROSCIENCE (2005)
Daytime sleep and performance following a zolpidem and melatonin cocktail
NJ Wesensten et al.
SLEEP (2005)
Orexin (hypocretin)/dynorphin neurons control GABAergic inputs to tuberomammillary neurons
KS Eriksson et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2004)
Wake-related activity of tuberomammillary neurons in rats
EM Ko et al.
BRAIN RESEARCH (2003)
Arousal systems
BE Jones
FRONTIERS IN BIOSCIENCE-LANDMARK (2003)
Fos immunoreactivity in hypocretin-synthesizing and hypocretin-1 receptor-expressing neurons: Effects of diurnal and nocturnal spontaneous waking, stress and hypocretin-1 administration
RA Espana et al.
NEUROSCIENCE (2003)
Tetrahydroisoquinolines as orexin receptor antagonists: Strategies for lead optimization by solution-phase chemistry
R Koberstein et al.
CHIMIA (2003)
Hypocretin/orexin excites hypocretin neurons via a local glutamate neuron - A potential mechanism for orchestrating the hypothalamic arousal system
Y Li et al.
NEURON (2002)
The locus coeruleus, Barrington's nucleus, and neural circuits of stress
AF Sved et al.
PHYSIOLOGY & BEHAVIOR (2002)
Orexins activate histaminergic neurons via the orexin 2 receptor
A Yamanaka et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2002)
The sleep switch: hypothalamic control of sleep and wakefulness
CB Saper et al.
TRENDS IN NEUROSCIENCES (2001)
Orexins (hypocretins) directly excite tuberomammillary neurons
L Bayer et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2001)
Differential expression of orexin receptors 1 and 2 in the rat brain
JN Marcus et al.
JOURNAL OF COMPARATIVE NEUROLOGY (2001)
Genetic ablation of orexin neurons in mice results in narcolepsy, hypophagia, and obesity
J Hara et al.
NEURON (2001)
Orexins/hypocretins excite basal forebrain cholinergic neurones
E Eggermann et al.
NEUROSCIENCE (2001)
Reduced number of hypocretin neurons in human narcolepsy
TC Thannickal et al.
NEURON (2000)