期刊
JOURNAL OF CHROMATOGRAPHY A
卷 1216, 期 24, 页码 4824-4830出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.chroma.2009.04.028
关键词
Ionic liquid; Solid-phase microextraction (SPME)
资金
- CUNY Collaborative Incentive [80209-07 13]
A new solid-phase microextraction (SPME) Procedure using an ionic liquid (IL) has been developed. Reusable IL-based SPME fiber was prepared for the first time by fixing IL through cross-linkage of IL impregnated silicone elastomer on the Surface of a fused silica fiber. 1-Ethoxyethyl-3-methylimidazloium bis(trifluoromethane) sulfonylimide ([EeMim][NTf2]) ionic liquid was employed as a demonstration and the prepared fiber was applied to the forensic headspace determination of methamphetamine (MAP) and amphetamine (AP) in human urine samples. Important extraction parameters including the concentration of salt and base in sample matrix, extraction temperature and extraction time were investigated and optimized. Combined with gas chromatography/mass spectrometry (GC/MS) working in selected ion monitoring (SIM) mode, the new method showed good linearity in the range of 20-1500 mu g L-1, good repeatability (RSD < 7.5% for MAP, and < 11.5% for AP. n = 6), and low detection limits (0.1 mu g L-1 for MAP and 0.5 mu g L-1 for AP). Feasibility of the method was evaluated by analyzing human Urine samples. Although IL-based SPME is still at the beginning of its development stage, the results obtained by this work showed that it is a promising simple, fast and sensitive sample preparation method. (C) 2009 Elsevier B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据