期刊
JOURNAL OF CHROMATOGRAPHY A
卷 1184, 期 1-2, 页码 132-142出版社
ELSEVIER
DOI: 10.1016/j.chroma.2007.08.088
关键词
sample preparation; liquid-phase microextraction; hollow fibers; review
Since 1999, substantial research has been devoted to the development of liquid-phase microextraction (LPME) based on porous hollow fibers. With this technology, target analytes are extracted from aqueous samples, through a thin supported liquid membrane (SLM) sustained in the pores in the wall of a porous hollow fiber, and further into a mu L volume of acceptor solution placed inside the lumen of the hollow fiber. After extraction, the acceptor solution is directly subjected to a final chemical analysis by liquid chromatography (HPLC), gas chromatography (GC), capillary electrophoresis (CE), or mass spectrometry (MS). In this review, LPME will be discussed with focus on extraction principles, historical development, fundamental theory, and performance. Also, major applications have been compiled, and recent forefront developments will be discussed. (c) 2007 Elsevier B.V. All rights reserved.
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