期刊
JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY
卷 54, 期 5, 页码 575-581出版社
WILEY
DOI: 10.1111/j.1469-7610.2012.02603.x
关键词
Conduct disorder; development
资金
- Division of Intramural Research Programs
- National Institute of Mental Health/NIH
Background: The presence of a large cavum septum pellucidum (CSP) has been previously associated with antisocial behavior/psychopathic traits in an adult community sample. Aims: The current study investigated the relationship between a large CSP and symptom severity in disruptive behavior disorders (DBD; conduct disorder and oppositional defiant disorder). Method: Structural MRI scans of youth with DBDs (N=32) and healthy comparison youth (N=27) were examined for the presence of a large CSP and if this was related to symptom severity. Results: Replicating previous results, a large CSP was associated with DBD diagnosis, proactive aggression, and level of psychopathic traits in youth. However, the presence of a large CSP was unrelated to aggression or psychopathic traits within the DBD sample. Conclusions: Early brain mal-development may increase the risk of a DBD diagnosis, but does not mark a particularly severe form of DBD within patients receiving these diagnoses.
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