期刊
JOURNAL OF CHILD NEUROLOGY
卷 29, 期 7, 页码 887-894出版社
SAGE PUBLICATIONS INC
DOI: 10.1177/0883073813491828
关键词
Pediatric stroke; arterial ischemic stroke; neuropsychological outcomes
资金
- Research Institute of the Nationwide Children's Hospital
- NIH
- National Health and Medical Research Council of Australia
- Research Institute at Nationwide Children's Hospital [231308]
- Murdoch Childrens Research Institute
- Victorian Governmental Operational Infrastructure Scheme
This study sought to investigate cognitive outcomes following pediatric arterial ischemic stroke and explore predictors. Participants included 36 children with perinatal or childhood arterial ischemic stroke and a comparison group of 15 children with asthma. Outcomes included cognitive ability, executive functions, and neurological function (Pediatric Stroke Outcome Measure). Magnetic resonance imaging measured lesion location and volume. Mean cognitive scores were at the low end of the average range. Children with arterial ischemic stroke performed significantly below normative populations and significantly below the asthma group on inhibitory control (Cohen's d = .68). Both the Pediatric Stroke Outcome Measure and lesion volume were negatively correlated with cognitive outcome (Spearman r = -.01 to -.42 Pediatric Stroke Outcome Measure; r = -.14 to -.32 Volume). Following arterial ischemic stroke, children performed at the low end of the average range on measures of cognitive functioning. Cognitive outcomes depend on a variety of factors.
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