期刊
JOURNAL OF CHILD NEUROLOGY
卷 26, 期 2, 页码 160-165出版社
SAGE PUBLICATIONS INC
DOI: 10.1177/0883073810376443
关键词
absence; ketogenic; diet; epilepsy; children; petit mal
资金
- Nutricia, Inc.
- Nutricia
- Atkins Nutritionals, Inc.
- Carson Harris Foundation
- Dr. Robert C. Atkins Foundation
- National Center for Research Resources/NIH [M01-RR00052]
Dietary therapies are established as beneficial for symptomatic generalized epilepsies such as Lennox-Gastaut syndrome; however, the outcome for idiopathic generalized epilepsy has never been specifically reported. The efficacy of the ketogenic and modified Atkins diet for childhood and juvenile absence epilepsy was evaluated from both historical literature review and patients treated at Johns Hopkins Hospital. Upon review of 17 published studies in which absence epilepsy was included as a patient subpopulation, approximately 69% of 133 with clear outcomes patients who received the ketogenic diet had a > 50% seizure reduction, and 34% of these patients became seizure free. At Johns Hopkins Hospital, the ketogenic diet (n = 8) and modified Atkins diet (n = 13) led to similar outcomes, with 18 (82%) having a > 50% seizure reduction, of which 10 (48%) had a > 90% seizure reduction and 4 (19%) were seizure free. Neither age at diet onset, number of anticonvulsants used previously, particular diet used, nor gender correlated with success.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据