期刊
JOURNAL OF CHEMOMETRICS
卷 25, 期 10, 页码 561-567出版社
WILEY
DOI: 10.1002/cem.1400
关键词
multivariate data analysis; metabolomics; proteomics; ANOVA-PCA; ASCA; permutation tests
类别
资金
- NWO, the Netherlands Organization for Scientific Research [864-02-001]
ANOVA-simultaneous component analysis (ASCA) is a recently developed tool to analyze multivariate data. In this paper, we enhance the explorative capability of ASCA by introducing a projection of the observations on the principal component subspace to visualize the variation among the measurements. We compare the significance of experimental effects for ASCA and ANOVA-principal component analysis (PCA), a similar tool to explore multivariate data, by using permutation tests. Furthermore, we quantify the quality of the loadings estimate obtained with ASCA and compare this with the loadings estimate obtained with ANOVA-PCA. Copyright (C) 2011 John Wiley & Sons, Ltd.
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