期刊
JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY
卷 84, 期 12, 页码 1762-1766出版社
WILEY
DOI: 10.1002/jctb.2241
关键词
oxidation; alkylaromatics; nitrogen-containing cation; N-hydroxyphthalimide; oxygen
类别
资金
- National Natural Science Foundation of China [20736010]
- Innovation Foundation of Dalian Institute of Chemical Physics, Chinese Academy of Sciences [K2007D6]
BACKGROUD: Direct oxidation of alkylaromatics to the corresponding aromatic ketone is an important process in the manufacture of perfumes, pharmaceuticals, flavors, dyes and agrochemicals. For example, tetralin is oxidized to produce 1-tetralinone, which is a key intermediate in the commercial production of 1-naphthol, 2-hydroxy-1-tetralone, aureolic acid antibiotics and other pharmaceuticals. RESULTS: In this investigation, it was found that alkylaromatics could be efficiently and selectively oxidized to the corresponding aromatic ketones when methyl violet was employed as a promotor in the presence of N-hydroxyphthalimide (NHPI); tetralin was oxidized with 89% conversion and 76% selectivity to 1-tetralinone under 0.3 MPa Of O-2 at 75 degrees C for 2.5 h. The effects of temperature, oxygen pressure, reaction time and additive inclusion were studied in detail. A possible reaction mechanism for tetralin oxidation has been proposed. CONCLUSION: It was demonstrated that methyl violet could efficiently promote the aerobic oxidation of alkylaromatics in the presence of NHPI under mild conditions. Further investigations indicated that the nitrogen cation had a crucial promotion effect in the oxidation process. (C) 2009 Society of Chemical Industry
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据