期刊
JOURNAL OF CHEMICAL RESEARCH
卷 -, 期 5, 页码 296-300出版社
SCIENCE REVIEWS 2000 LTD
DOI: 10.3184/030823410X12746350585058
关键词
heteroaryl-substituted thiazolidinone; configuration; diastereomer; NOE-difference; X-ray crystallography
Some heteroaryl-substituted thiazolidin-4-one derivatives have been synthesised starting from thiophenecarbox-aldehydes, 2-amino-6-methylpyridine and 2-mercaptoacetic acid. However, the use of 2-mercaptopropanoic acid gave the thiazolidinone derivatives as a mixture of cis-and trans-isomers. The configuration of both the cis-and trans-isomers has been established by NOE-difference experiments. Furthermore, the stereochemistry of one of the trans isomers was established by X-ray crystallography.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据