期刊
NEURON
卷 85, 期 3, 页码 450-452出版社
CELL PRESS
DOI: 10.1016/j.neuron.2015.01.021
关键词
-
资金
- Canadian Institutes of Health Research Funding Source: Medline
In this issue of Neuron, Chakrabarty et al. (2015) and Guillot-Sestier et al. (2015) reveal that the anti-inflammatory cytokine IL-10 inhibits A beta clearance by microglia, worsening cognitive decline in mouse models of Alzheimer's disease (AD). These studies provide further support that pro-inflammatory signaling is an innate immune defense mechanism in AD.
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