期刊
JOURNAL OF CHEMICAL PHYSICS
卷 136, 期 20, 页码 -出版社
AMER INST PHYSICS
DOI: 10.1063/1.4722080
关键词
-
资金
- Academy of Finland through its COMP Center of Excellence and Transpoly Consortium
- Finnish Doctoral Programme in Computational Sciences (FICS)
- Finnish Foundation for Technology Promotion (TES)
We study the driven translocation of polymers under time-dependent driving forces using N-particle Langevin dynamics simulations. We consider the force to be either sinusoidally oscillating in time or dichotomic noise with exponential correlation time, to mimic both plausible experimental setups and naturally occurring biological conditions. In addition, we consider both the case of purely repulsive polymer-pore interactions and the case with additional attractive polymer-pore interactions, typically occurring inside biological pores. We find that the nature of the interaction fundamentally affects the translocation dynamics. For the non-attractive pore, the translocation time crosses over to a fast translocation regime as the frequency of the driving force decreases. In the attractive pore case, because of a free energy well induced inside the pore, the translocation time can be aminimum at the optimal frequency of the force, the so-called resonant activation. In the latter case, we examine the effect of various physical parameters on the resonant activation, and explain our observations using simple theoretical arguments. (C) 2012 American Institute of Physics. [http://dx.doi.org/10.1063/1.4722080]
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据