期刊
JOURNAL OF CHEMICAL PHYSICS
卷 132, 期 19, 页码 -出版社
AMER INST PHYSICS
DOI: 10.1063/1.3408289
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资金
- Development of Systems and Technology for Advanced Measurement and Analysis of Japan Science and Technology Corporation
Hydration structures at biomolecular surfaces are essential for understanding the mechanisms of the various biofunctions and stability of biomolecules. Here, we demonstrate the measurement of local hydration structures using an atomic force microscopy system equipped with a low-noise deflection sensor. We applied this method to the analysis of the muscovite mica/water interface and succeeded in visualizing a hydration structure that is site-specific on a crystal. Furthermore, at the biomolecule/buffer solution interface, we found surface hydration layers that are more packed than those at the muscovite mica/water interface. (C) 2010 American Institute of Physics. [doi: 10.1063/1.3408289]
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