Thermodynamic Study of Phenyl Salicylate Solutions in Aprotic Solvents at Different Temperatures

Phenyl salicylate is employed as a nervous system depressant as well as an intestinal antiseptic owing to its antibacterial activity upon hydrolysis in the small intestine. Various partial molar quantifies, namely, apparent molar volume (V-phi), partial molar volume (V-m degrees), thermal expansion coefficient (alpha(2)), and (partial derivative V-2(m)degrees/partial derivative T-2), of phenyl salicylate in aprotic solvents, i.e., acetonitrile, dimethyl sulfoxide, tetrahydrofuran, and 1,4-dioxane, at T = (293.15 to 313.15) K have been determined. The density and viscosity data were obtained with the help of a vibrating-tube densimeter and viscometer in a concentrarion range of (9.6.10(-3) to 33.0.10(-3)) mol . kg(-1). The viscosity data have been analyzed using the Jones-Dole equation and the derived parameter B has also been interpreted in terms of solute-solvent interactions.