相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。The addition of low-dose-rate brachytherapy and androgen-deprivation therapy decreases biochemical failure and prostate cancer death compared with dose-escalated external-beam radiation therapy for high-risk prostate cancer
Mark Shilkrut et al.
CANCER (2013)
Copy number alterations of c-MYC and PTEN are prognostic factors for relapse after prostate cancer radiotherapy
Gaetano Zafarana et al.
CANCER (2012)
PTEN Deletion in Prostate Cancer Cells Does Not Associate with Loss of RAD51 Function: Implications for Radiotherapy and Chemotherapy
Michael Fraser et al.
CLINICAL CANCER RESEARCH (2012)
Insulin-like growth factor 1 stimulation of androgen receptor activity requires β1A integrins
Aejaz Sayeed et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2012)
β1 Integrin/FAK/cortactin signaling is essential for human head and neck cancer resistance to radiotherapy
Iris Eke et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
JNK and PTEN cooperatively control the development of invasive adenocarcinoma of the prostate
Anette Huebner et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
β1 integrin deletion enhances progression of prostate cancer in the TRAMP mouse model
Kim Moran-Jones et al.
SCIENTIFIC REPORTS (2012)
The role of JNK in the development of hepatocellular carcinoma
Madhumita Das et al.
GENES & DEVELOPMENT (2011)
A phase 1, multicenter, open-label study of the safety of two dose levels of a human monoclonal antibody to human αv integrins, intetumumab, in combination with docetaxel and prednisone in patients with castrate-resistant metastatic prostate cancer
Franklin M. Chu et al.
INVESTIGATIONAL NEW DRUGS (2011)
Breast Cancer Cells in Three-dimensional Culture Display an Enhanced Radioresponse after Coordinate Targeting of Integrin α5β1 and Fibronectin
Jin-Min Nam et al.
CANCER RESEARCH (2010)
Diverse somatic mutation patterns and pathway alterations in human cancers
Zhengyan Kan et al.
NATURE (2010)
Coadministration of a Tumor-Penetrating Peptide Enhances the Efficacy of Cancer Drugs
Kazuki N. Sugahara et al.
SCIENCE (2010)
Tissue-Penetrating Delivery of Compounds and Nanoparticles into Tumors
Kazuki N. Sugahara et al.
CANCER CELL (2009)
β1 Integrin Cytoplasmic Variants Differentially Regulate Expression of the Antiangiogenic Extracellular Matrix Protein Thrombospondin 1
Hira Lal Goel et al.
CANCER RESEARCH (2009)
Integrin β1-focal adhesion kinase signaling directs the proliferation of metastatic cancer cells disseminated in the lungs
Tsukasa Shibue et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Conditional deletion of insulin-like growth factor-I receptor in prostate epithelium
Brent W. Sutherland et al.
CANCER RESEARCH (2008)
β1 integrin inhibition dramatically enhances radiotherapy efficacy in human breast cancer xenografts
Catherine C. Park et al.
CANCER RESEARCH (2008)
Volociximab, a Chimeric Monoclonal Antibody that Specifically Binds α5β1 Integrin: A Phase I, Pharmacokinetic, and Biological Correlative Study
Alejandro D. Ricart et al.
CLINICAL CANCER RESEARCH (2008)
Prostate carcinoma and radiation therapy: therapeutic treatment resistance and strategies for targeted therapeutic intervention
T. J. FitzGerald et al.
EXPERT REVIEW OF ANTICANCER THERAPY (2008)
The integrin - Growth factor receptor duet
Naved Alam et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2007)
A function blocking anti-mouse integrin α5β1 antibody inhibits angiogenesis and impedes tumor growth in vivo
Vinay Bhaskar et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2007)
An update of the phase III trial comparing whole pelvic to prostate only radiotherapy and neoadjuvant to adjuvant total androgen suppression: Updated analysis of RTOG 94-13, with emphasis on unexpected hormone/radiation interactions
Colleen A. Lawton et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2007)
AFAP-110 is overexpressed in prostate cancer and contributes to turnorigenic growth by regulating focal contacts
Jing Zhang et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Increased tumor cell dissemination and cellular senescence in the absence of β1-integrin function
Angelika Kren et al.
EMBO JOURNAL (2007)
Role of mitogen-activated protein kinase kinase 4 in cancer
A. J. Whitmarsh et al.
ONCOGENE (2007)
Insulin-like growth factor-I receptor signaling blockade combined with radiation
Gregory W. Allen et al.
CANCER RESEARCH (2007)
Increased β1 integrin is associated with decreased survival in invasive breast cancer
Evelyn S. Yao et al.
CANCER RESEARCH (2007)
The JNK signal transduction pathway
Claire R. Weston et al.
CURRENT OPINION IN CELL BIOLOGY (2007)
Identification of the JNK signaling pathway as a functional target of the tumor suppressor PTEN
Igor Vivanco et al.
CANCER CELL (2007)
β1 integrin inhibitory antibody induces apoptosis of breast cancer cells, inhibits growth, and distinguishes malignant from normal phenotype in three dimensional cultures and in vivo
CC Park et al.
CANCER RESEARCH (2006)
Targeting ECM-integrin interaction with liposome-encapsulated small interfering RNAs inhibits the growth of human prostate cancer in a bone xenograft imaging model
K Bisanz et al.
MOLECULAR THERAPY (2005)
Receptor for RACK1 mediates activation of JNK by protein kinase C
P Lopez-Bergami et al.
MOLECULAR CELL (2005)
Interactions of the integrin subunit β1A with protein kinase B/Akt, p130Cas and paxillin contribute to regulation of radiation survival
J Seidler et al.
RADIOTHERAPY AND ONCOLOGY (2005)
β1A integrin expression is required for type 1 insulin-like growth factor receptor mitogenic and transforming activities and localization to focal contacts
HL Goel et al.
CANCER RESEARCH (2005)
beta 1 integrin function in vivo: Adhesion, migration and more
C Brakebusch et al.
CANCER AND METASTASIS REVIEWS (2005)
Using mouse genetics to dissect the cellular target of radiation in the GI syndrome
DG Kirsch et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2005)
Selective modulation of type 1 insulin-like growth factor receptor signaling and functions by β1 integrins
HL Goel et al.
JOURNAL OF CELL BIOLOGY (2004)
Targeted disruption of β1-integrin in a transgenic mouse model of human breast cancer reveals an essential role in mammary tumor induction
DE White et al.
CANCER CELL (2004)
INK potentiates TNF-stimulated necrosis by increasing the production of cytotoxic reactive oxygen species
JJ Ventura et al.
GENES & DEVELOPMENT (2004)
The igf-1 receptor in cancer biology
R Baserga et al.
INTERNATIONAL JOURNAL OF CANCER (2003)
Fibronectin protects prostate cancer cells from tumor necrosis factor-α-induced apoptosis via the AKT/survivin pathway
M Fornaro et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Integrins: Bidirectional, allosteric signaling machines
RO Hynes
CELL (2002)
Generation of a prostate epithelial cell-specific Cre transgenic mouse model for tissue-specific gene ablation
XT Wu et al.
MECHANISMS OF DEVELOPMENT (2001)
Conditional ablation of β1 integrin in skin:: Severe defects in epidermal proliferation, basement membrane formation, and hair follicle invagination
S Raghavan et al.
JOURNAL OF CELL BIOLOGY (2000)